Testosterone has been and remains the most potent drug, with respect to
muscle mass, that is, put simply - the most powerful anabolic. However,
testosterone has methyltestosterone as well) another difference, which sharply
distinguishes it from the total number. And that, in fact, often they mean when
they talk about the "androgenic activity." This is the ability of
testosterone to turn with the direct involvement of the
enzyme 5-a reductase in the di-gidrotestosteron (DHT). In the case of
methyltestosterone this transformation takes place in the
17-methyl-dihydrotestosterone, which is actually more powerful DHT. Good or bad?
Paradoxically, but both good and bad.
Testosterone is not responsible for the fact that an athlete is gaining fat
during the course and collects excess water. If this were so, all men with
elevated levels of testosterone in the blood would suffer from obesity. On the
contrary - are prone to obesity as precisely those men who have testosterone
levels below normal. As for the "pharmacological component", the
responsibility for such unwanted metamorphosis taking place in the male body
lying on estradiol - estrogen, which becomes "the most important"
male sex hormone. This is certainly true about water retention, fat
accumulation with respect to, here, as it turns out, all is not so simple.
First, it is worth noting that testosterone contributes to enhance the process
of lipolysis. It contributes, through the activation of a-2-adrenergic
receptors, which gives approximately the same effect as the activation of
p-2-adrenergic receptors by clenbuterol. Secondly, very interesting is the fact
that moderate aromatization just gives "green light" to incorporate
fat-burning properties of testosterone - the use of androgen on the background
of aromatase inhibitors did not reveal its fat burning abilities.
An indirect confirmation of this fact is also an experiment on laboratory rats,
in which the test subject had injected
17-3-estradiol. It was found that the drug at a dosage of 500 micrograms per
kilogram of body weight leads to a significant reduction in body fat in males.
Of course, the rats are not humans, but still ...
From the
foregoing it can be concluded that only excessively high levels of estradiol in
the blood of men can lead to excessive accumulation of fat. The basic
responsibility for it does not have hormonal changes, and intemperance in
eating - at the stage of muscle gains some athletes find it possible
to not limit oneself to anything.
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