One of the most misunderstood substances in the world of steroids is
the ester, is it actually defines how a particular solution of testosterone -
cypionate, enanthate, Sustanon. If you quickly go over the pharmacological
Internet, you will find many articles in which some forms of testosterone are
declared significantly more effective than others. The reasoning for this is
always very similar, and usually futile. In this article we will try to take
another look at the esters and the way they act onsteroids.
What is
ester and how it works?
You can be sure that if you are interested in anabolics, you have
repeatedly pointed out the similarity of many labels. Take, for instance,
testosterone. You can find drugs like testosterone cypionate, enanthate,
propionate, caproate, isocaproate, decanoate, acetate, the list goes on and on.
In all cases, a common element - the hormone testosterone, modified by the
addition of ester (enanthate, propionate, etc.) in its structure. In the
presence of an explicit common structural element of the question is: what is
the difference from one another, all these modifications of testosterone in
relation to their use in bodybuilding? Ether is a chain composed primarily of
carbon and hydrogen atoms. In most cases, this chain of clinging to the steroid
hormones in the 17th position of the carbon atom (beta orientation),
in some cases, steroids are kept aired on the
third position (within the scope of this article the
exact position of the ether is not critical).
Such accession of ester (etherification) gives all injectable anabolic /
androgenic steroids is one important feature - slow release of
steroid into the body itself from the injection site. This is because the air
significantly reduces the solubility of the steroid in water and significantly
increases its lipid (fat) solubility. This leads to the formation of
a temporary supply of the drug in muscle tissue, and further release it into
the blood in small quantities. In most cases, the longer the ester chain, the
lower the solubility of the steroid in water and the slower the drug begins to
take part in the main exchange. Slowing down the selection of the drug in the
blood - a big advantage for steroid courses, as free testosterone (and other
steroid hormones) in the human organism is living a very small amount of time
(several hours). This necessitates an unpleasant procedure for injection of the
drug several times a day on a schedule for keeping constant level of hormone in
the blood. When added to the drug ether, the frequency of injection can be
greatly reduced. Without the use of esters of steroid therapy would be much
more time-consuming and unpleasant issue.
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